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Dr. Konstantina Yannakopoulou
Institute of Physical Chemistry, NCSR "Demokritos", Aghia Paraskevi 15310- Athens Greece
tel: +30-210-6503796; fax: +30-210-651176: e-mail:dyanna"at"chem.demokritos.gr
Konstantina Yannakopoulou graduated from the Chemistry Department, University of Athens
in 1981. She earned a research scholarship in NRC “Demokritos” where she stayed
for two semesters (1982) and then she moved to South Carolina, US, where she
earned a MSc degree in Chemistry with Prof. R. A. Abramovitch at Clemson
University, USA (1985) (Thesis title: "Remote Intramolecular
Functionalization of Arylnitrenium Ions. Seven-membered Ring Formation”.
She then obtained her PhD degree in Chemistry with Prof. A. R. Katritzky at the
University of Florida,
USA
(1988) (Dissertation title: “N-(α-Aminoalkyl)benzotriazoles: Equilibria and Reactions”). After an eight-month post-doctoral stay at the
same laboratory she joined the Institute
of Physical Chemistry,
NCSR “Demokritos” in 1989, she was elected as staff-member in 1996 and promoted
to Researcher A in 2006. Her research interests focus on molecular
structure-properties relations and particularly on the characterization of
host/guest interactions, stability and equilibria of cyclodextrin-guest
systems, synthetic modifications of cyclodextrins to functional host molecules
and their bio and nano applications (nucleotide
and DNA carriers, cell penetrating agents and also as blockers of specific
pore-forming lethal toxins). The research focus has also been recently expanded
to photoactive molecules (such as porphyrins) and their covalent conjugates
with cyclodextrins as multifunctional bioactive hosts systems combining singlet
oxygen production, drug transport and fluorescence imaging for chemotoxic and
photodynamic applications. She has authored and co-authored 72 papers in
international refereed journals (including Angew. Chem., Chem. Eur. J.,
Chem. Asian J., J. Org. Chem., Org. Biomol. Chem., Carbohydr. Res., Eur. J. Org.
Chem.), as well as a book chapter, and has presented her research in more
than 60 conferences. Her work has received >980 hetero-citations (Web of
Science). Since 1991 she has been the Scientist in Charge of the high
resolution NMR Lab for liquid samples for the Institute, and she has
co-organized and co-maintained the NMR infrastructure, the service and the
contacts with private companies and academic institutions. She is currently the
coordinator of the 4-year European project PEOPLE, ITN “Novel multifunctional cyclodextrin-based
nanocarriers for drug encapsulation and
delivery as a strategy to overcome current therapeutic drawbacks” ,CYCLON, comprising
nine groups throughout Europe. Recently she served a Local Organising
Committee member for the International NMR Conference EUROMAR 2013
(Crete, Greece, June 30 to July 5, 2013).
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