Luminescence Laboratory of Organic Compounds Group

1. Asymmetric synthesis of β-substituted δ-ketoesters via Michael additions of SAMP/RAMP-hydrazones to α,β-unsaturated esters. Virtually complete 1,6-asymmetric induction, D. Enders and K. Papadopoulos, Tetrahedron Lett.  24, 4967 (1983).

2. Synthesis of diastereo- and enantiomerically pure α-amino γ-oxocarboxylates by reaction of acyliminoacetates with enamines derived from 6-membered ketones, R. Kober, K. Papadopoulos, W. Miltz, D. Enders, W. Steglich, Tetrahedron 41, 1693 (1985).

3. Asymmetric Michael additions via SAMP/RAMP-hydrazones. Anti-diastereo- and enantioselective synthesis of 3,4-disubstituted 5-oxoalkanoates, D Enders, K. Papadopoulos, B. Rendenbach, Tetrahedron Lett.  27, 3471  (1986).

4. Chemiluminescence in organized molecular assemblies.  Chemiluminescence of lucigenin in Lyso-PAF (C16).  E. Varveri, A.E. Mantaka-Marketou, K. Papadopoulos, J. Nikokavouras,  J. Photochem. Photobiol. A: Chem., 66, 113 (1992).

5. Enzyme catalyzed highly stereoselective C-C bond forming reactions, D. Enders, B. Bockstiegel, H. Dyker, U. Jegelka, D. Kownatka, H. Kuhlmann, D. Mannes, J. Tiebes and K. Papadopoulos, DECHEMA Monographie, 129, 209 (1993).

6. Asymmetric Michael additions via SAMP-/RAMP-hydrazones. Enantioselective synthesis of 2-substituted 4-oxosulfones.  D. Enders, K. Papadopoulos and E. Herdtweck, Tetrahedron, 49, 1821 (1993).

7. Synthesis of novel protected hemiaminal N-methoxymethyl-N'-methyl- 9,9'-biacridylidene from Lucigenin.  K. Papadopoulos and J. Nikokavouras, Tetrahedron Lett.,  34, 1371 (1993).

8. Synthesis of novel N,N'-dialkyl- 9,9'-biacridylidenes and 9,9'-biacridinium nitrates containing long alkyl chains.  K. Papadopoulos and J. Nikokavouras, J. Prakt. Chemie-Chem. Zeitung,  335, 633 (1993).

9. Chemiluminescence of N, N'-dialkyl-9,9'-biacridinium nitrates in aqueous and non aqueous systems, K. Papadopoulos, J. Hadjianestis and J. Nikokavouras,  J. Photochem. Photobiol. A: Chem., 75, 91 (1993).

10. Chemiluminescence in organized molecular assemblies. Chemiluminescence of lucigenin derivatives containing long alkyl chains in micellar media. K. Papadopoulos, S. Spartalis and J. Nikokavouras, Anal. Chim. Acta, 290, 179 (1994).

11. Chemiluminescence of N,N'-dialkyl-9,9'-biacridylidenes in homogeneous and micellar media. K. Papadopoulos, S. Spartalis, J. Nikokavouras, D. Dimotikali and K. Mitsoulis, J. Photochem. Photobiol. A: Chem. 83, 15 (1994).

12. Reactions of lucigenin in protic solvents in the presence of amines, K. Papadopoulos, J. Nikokavouras, D. Dimotikali, J. Prakt. Chemie-Chem. Zeitung, 336, 506  (1994).

13. Chemiluminescence of protected hemiaminal N-methoxymethyl-N'-methyl-9,9'-biacridylidene in organized molecular assemblies and organic solvents, K. Papadopoulos, K. Mitsoulis , J. Nikokavouras, D. Dimotikali,  Anal. Chim. Acta,  304, 91 (1995).

14. Asymmetric Michael additions via SAMP/RAMP-hydrazones. Enantioselective synthesis of 2-substituted 4-oxophosphonates.  D. Enders, H. Wahl and K. Papadopoulos, Liebigs Ann. Chem. 1995, 1177.

15. Chemiluminescence of novel acridans.  K. Papadopoulos, J. Nikokavouras, D. Dimotikali, Chim. Chronika, N. Series, 25, 35 (1996).

16. Chemiluminescence of photolyzed or radiolyzed acridine. K. Papadopoulos, J. Nikokavouras and D. Dimotikali, J. Photochem. Photobiol. A: Chem., 103, 55 (1997).

17. Diastereo- and enantioselective synthesis of 2,3- and 1,2-disubstituted 4-oxophosphonates via asymmetric Michael-addition. D. Enders, H. Wahl and K. Papadopoulos, Tetrahedron, 53, 12961 (1997).

18. Electrogenerated chemiluminescence of phthalic hydrazide in the presence of fluorescein and cetyltrimethylammonium halides and pseudohalides. J. Hrbáč, J. Lasovský, K. Papadopoulos, J. Nikokavouras, J. Biolumin. Chemilumin, 13 (4) 222 (1998). Full text in: Bioluminescence and chemiluminescence: Perspectives for the 21st century. J. Wiley and Sons, Chichester, New York (1999).

19. Radiochemiluminescence of acridones and alkyl acridines. K. Papadopoulos, J. Lignos,    M.    Stamatakis, D. Dimotikali, J. Nikokavouras, J. Photochem. Photobiol. A: Chem., 115, 155 (1998).  

20. Sensitized chemiluminescence of long alkyl chain energy transfer donors and acceptors in micellar media, K. Papadopoulos, A. Chantron, J. Nikokavouras, J. Hrbac, J. Lasovsky, J. Photochem. Photbiol. A: Chem. 116, 137 (1998).

21. Chemiluminescence at liquid-liquid interfaces. Enhanced chemiluminescence of lucigenin and long alkyl Lucigenins. K. Papadopoulos, S. Spartalis and J. Nikokavouras, J. Photochem. Photοbiol. A: Chem., 119, 115 (1998).

22. Photo- and radiochemiluminescence: Reductive chemiluminescence of lucigenin by photo- or radiooxygenated amines and amides.  K. Papadopoulos, T. Triantis, D. Dimotikali, J. Nikokavouras, J. Photochem. Photοbiol. A: Chem. 124, 85-90 (1999).

23. Radiochemiluminescence of carboxyquinolines, K. Papadopoulos, T. Triantis, D. Dimotikali, J. Nikokavouras, J. Photochem. Photοbiol. A: Chem. 131, 55-60 (2000).

24. Radio- and photostoragechemiluminescence: Analytical Prospects, K. Papadopoulos, T. Triantis, D. Dimotikali, J. Nikokavouras, Anal. Chim. Acta,  423, 239-245 (2000).

25. Evaluation of antioxidant activity by photostoragechemiluminescence, K. Papadopoulos, T. Triantis, D. Dimotikali, J. Nikokavouras, Anal. Chim. Acta,  433, 263-268 (2001).

26. Photo-, radio- and sonostoragechemiluminescence of buckminsterfullerenes, C60. K. Papadopoulos, T. Triantis, S. Boyatzis, D. Dimotikali, J. Nikokavouras, J. Photochem. Photοbiol. A: Chem. 143, 93-97 (2001).

27. Studies on the photostoragechemiluminescence of aromatic ketones with reactive oxygen species. Prospects for analytical applications, K. Papadopoulos,  T. Triantis,  K. Tsaggaraki, D. Dimotikali, N. Iftimie, A. Meghea, J. Photochem. Photοbiol. A: Chem. 152, 11-16  (2002).

28. Investigations of the adulteration of extra virgin olive oils with seed oils using their weak chemiluminescence, K. Papadopoulos, T. Triantis, C. Tzikis, A. Nikokavoura and D. Dimotikali, Anal. Chim. Acta,  464, 135-140 (2002).

29. Comparative studies on the antioxidant activity of aqueous extracts of olive oils and seed oils using chemiluminescence, K. Papadopoulos, T. Triantis, E. Yannakopoulou, A. Nikokavoura, D. Dimotikali, Anal. Chim. Acta, 494, 41-47 (2003).

30. Oxidative stress quantifying in biosystems. Chemiluminescence testing of the antioxidant activity of some molecules of biological interest, A. Meghea, N. Iftimie, M. Giurginca, K. Papadopoulos, Rev. de Chimie, 54, 885 - 887 (2003).

31. The quantification of the oxidative stress in biosystems IΙΙ. Βehavior of vitamins during peroxidation and UV irradiation, N. Iftimie, M. Giurginca, A. Meghea , K. Papadopoulos, Rev. de Chimie, 55,  92-94 (2004).

32. Conversion of epiandrosterone into 17β-amino-5a-androstane, M.I. Merlani, M.G. Davitshvili, N. Sh. Nadaraia, M.I. Sikaharulidze, K. Papadopoulos, Chemistry of Natural Compounds. 40, 144 - 146 (2004).

33. Some derivatives of 5a-ketosteroid hydrazones: Synthesis from Tigogenin and antituberculosis activity, M.I. Merlani, E.P. Kemertelidze, K. Papadopoulos, N.I. Menshova, Rus. J. Bioorg.  Chem, 30, 552 - 557 (2004).

34. Sensitized chemiluminescence in micellar mixtures of phthalhydrazide and selected dyes, Jan Hrbáč, Dana Sichertová, Martina Bancířová, Jan Lasovský, Kyriakos Papadopoulos, John Nikokavouras, J. Photochem. Photοbiol. A: Chem., 167, 169-175 (2004).

35. Synthesis and chemiluminescent properties of novel biotinylated acridinium esters, K. Agiamarnioti, T. Triantis, K. Papadopoulos, D. Dimotikali, Acta Chim. Slov, 51, 67 - 76  (2004).

36. Synthesis and fluorescent properties of novel biotinylated labels. Prospects for application in bioanalytical detections, K. Agiamarnioti , T. Triantis, K. Papadopoulos D. Dimotikali, J. Photochem. Photοbiol. A: Chem , 172, 215-221 (2005).

37. Novel Biotinylated Acridinium Derivatives: New Reagents for Fluorescence  Immunoassays and Proteomics, A. Scorilas, K. Agiamarnioti, K. Papadopoulos, Clin. Chim. Acta, 357, 159 - 167 (2005).  

38. Investigations on the antioxidant activity of aqueous extracts of fruits and vegetables on superoxide radicals using chemiluminescence techniques, K. Papadopoulos, T. Triantis, A. Stelakis, D. Dimotikali, Anal. Chim. Acta, 536, 101-105 (2005).

39. 10-(2-biotinyloxyethyl)-9-acridone. A novel fluorescent label for (strept)avidin-biotin based assays, K. Agiamarnioti , T. Triantis, K. Papadopoulos, A. Scorilas,  J. Photochem. Photοbiol. A: Chem, 181, 126-131 (2006).

40. Synthesis of novel steroidal isonicotinoylhydrazones and thiosemicarbazones from tigogenin, M. I. Merlani, L. Sh. Amiranashvili, M. G. Davitishvili, E. P. Kemertelidze,1 K. Papadopoulos,  and E. Yannakopoulou, Chemistry of Natural Compounds, 42, 194-197 (2006).

41. Synthesis of 17a-amino-5a-androst-2-ene from epiandrosterone, M. I. Merlani, L. Sh. Amiranashvili, E. P. Kemertelidze, K. Papadopoulos and E. Yannakopoulou, Chemistry of Natural Compounds, Vol. 42, 313-315 (2006).

42. Chemiluminescent studies on the antioxidant activity of amino acids, T.M. Triantis, E. Yannakopoulou, A. Nikokavoura, D. Dimotikali and K. Papadopoulos, Anal. Chim.  Acta, 591 (2007) 106-111.

43. Studies on the catalytic activity of novel hybridized chiral organo-inorganic catalysts for epoxidation and alkylation reactions, O. Lanitou, D. Dimotikali, E. Yannakopoulou and K. Papadopoulos, Chem. Eng.  J, 134 (2007) 72-77.

44. Carbon electrodes modified by nanoscopic Iron (III) Oxides to assemble chemical sensors for the hydrogen peroxide amperometric detection., Jan Hrbac, Vladimir Halouzka, Radek Zboril, Kyriakos Papadopoulos and Theodor Triantis, Electroanalysis, 19 (2007) 1850-1854.

45. Synthesis and antioxidant activity of 3-(3,4-dihydroxyphenyl)glyceric acid. Monomer of a biologically active polyether isolated from Symphytum asperum and S. caucasicum, M. Merlani, V. Barbakadze, L. Gogilashvili, L. Amiranashvili, K. Mulkijanyan, E. Yannakopoulou, K. Papadopoulos, D. Christodouleas, J. Planta Medica, 74 (2008) 1167-1168.

46. Sensitized chemiluminescence of luminol catalyzed by colloidal dispersions of nanometer-sized ferric oxides, T.M. Triantis, K. Papadopoulos, E. Yannakopoulou, D. Dimotikali, J. Hrbáč, R. Zbořil, Chem  Eng.  J, 144 (2008) 483-488.

47. Development and validation of a chemiluminogenic method for the evaluation of antioxidant activity of hydrophilic and hydrophobic antioxidants, A.C. Calokerinos, D. Christodouleas, C. Fotakis, K. Papadopoulos, E. Yannakopoulou, Anal. Chim.  Acta, in press (2009).