Υποτροφίες

 

ΙΝΣΤΙΤΟΥΤΟ ΦΥΣΙΚΟΧΗΜΕΙΑΣ


 
Διαλέξεις / Σεμινάρια

 

Την Τετάρτη 20 Νοεμβρίου 2013 και ώρα 11 π.μ.

ο καθηγητής Θωμάς Ανθόπουλος

Department of Physics and Centre for Plastic Electronics, Imperial College London, Blackett Laboratory, London, UK

 θα δώσει διάλεξη με τίτλο:

 "New materials and fabrication paradigms for plastic electronics"

στο Αμφιθέατρο του τομέα Προηγμένων υλικών του Ινστιτούτου Προηγμένων Υλικών, Φυσικοχημικών Διεργασιών, Νανοτεχνολογίας και Μικροσυστημάτων (Κτίριο 8).

 


Την Παρασκευή 15 Νοεμβρίου 2013 και ώρα 13:00, η Δρ. Βάσω Κωστούρου (ΕΚΕΒΕ "Αλ. Φλέμινγκ") 

 

θα δώσει διάλεξη στο Αμφιθέατρο Φυσικοχημείας - Βιολογίας με τίτλο:

"The role of adhension in angiogenesis"

Η διάλεξη οργανώνεται από το Ινστιτούτο Βιοεπιστημών και εφαρμογών και την Δρ. Η. Γεωργούση

 

 
 

Την Παρασκευή 1 Νοεμβρίου και ώρα 13:00,

η αναπληρώτρια καθηγήτρια Ζωή Λυγερού (Πανεπιστήμιο Πατρών)

θα δώσει διάλεξη στο Αμφιθέατρο Φυσικοχημείας - Βιολογίας με τίτλο:

"Maintaining a stable genome: views into live cells"

Η διάλεξη οργανώνεται από το Ινστιτούτο Βιοεπιστημών και εφαρμογών και την Δρ. Η. Γεωργούση


 
Εργασία Στο ΙΦΧ

 

29/07/2013 Πρόσκληση εκδήλωσης ενδιαφέροντος για υποψήφιο διδάκτορα



 
Ανακοινώσεις

_

Πρόσκληση Εκδήλωσης Ενδιαφέροντος για Έμπειρο Επιστημονικό Συνεργάτη / Fellow for MARIE CURIE SANAD project

 

 ΔΙΑΤΜΗΜΑΤΙΚΟ ΠΡΟΓΡΑΜΜΑ ΜΕΤΑΠΤΥΧΙΑΚΩΝ ΣΠΟΥΔΩΝ «ΚΛΙΝΙΚΗ ΒΙΟΧΗΜΕΙΑ – ΜΟΡΙΑΚΗ ΔΙΑΓΝΩΣΤΙΚΗ»

Προκήρυξη θέσεων Μεταπτυχιακών Φοιτητών
για το Ακαδημαϊκό Έτος 2012-2013

 

15/07/2012 Πρόσκληση Εκδήλωσης Ενδιαφέροντος για Επιστημονικό Συνεργάτη

15/07/2012 Πρόσκληση Εκδήλωσης Ενδιαφέροντος για Θέση Μεταδιδακτορικού Συνεργάτη

 

ΠΡΟΚΗΡΥΞΗ ΤΟΥ ΔΙΑΤΜΗΜΑΤΙΚΟΥ

ΠΡΟΓΡΑΜΜΑΤΟΣ ΜΕΤΑΠΤΥΧΙΑΚΩΝ ΣΠΟΥΔΩΝ (Π.Μ.Σ.)

 «ΚΛΙΝΙΚΗ ΒΙΟΧΗΜΕΙΑ-ΜΟΡΙΑΚΗ ΔΙΑΓΝΩΣΤΙΚΗ»

 

Προκήρυξη χορήγησης υποτροφίας για την εκπόνηση διδακτορικής διατριβής


 
Special Events


 

Institute of Physical Chemistry

Institute of Physical Chemistry

Transport of matter phenomena in polymers
There are no translations available.


Personnel

Dr. Merope Sanopoulou: research director

Dr. Kyriaki Papadokostaki: principal researcher

Dr. J.H. Petropoulos: emeritus researcher

Dr. Dimitrios Soulas (post-doctoral collaborating researcher)

Mayra Konidari (PhD student)

Athanasia Panou ( PhD student)


Albana Hasimi, Kyriaki Manoli, Aristea Stavropoulou, Maria Herouvim (Previous members)



Research Objectives/Activities

Research focuses on micromolecular sorption and transport in polymeric materials by a combination of theoretical and experimental approaches. The aim of this work is to help create the basic scientific background for the optimization of the design of polymeric materials for important applications (controlled release systems, permselective membranes, packaging, chemical sensors etc).


Current research activities include


Polymer-based controlled release systems

Development of controlled release devices aims at the regulated, prolonged delivery of drugs, agrochemicals or other bioactive agents. Matrix-type controlled release devices consist of a swellable polymer matrix incorporating the requisite bioactive solute and are activated by the ingress of water when placed in an aqueous environment. Research of our group in this area aims at the optimization of the design of these devices, in order to alleviate their main drawback of continuous decline of dose rate. Theoretical work focuses on the development of advanced, realistic models, simulating the release performance of single-layer as well as multilayered devices. Experimental work includes (i) Validation of models against experiment, based on model experimental systems (ii) Effect of chemical or physical treatment on drug release from hydrogels (iii) Effect of osmotic excipients on drug release from hydrophobic matrices (iv) Development of multilaminate devices which constitute a promising design strategy for approaching the desired constant dose rate.


Theoretical prediction of uniform release rate by the use of multilaminate matrix controlled release devices. Under the conditions of the example shown here, the single layer matrix with uniform distribution of embedded solute (–––) is characterized by a continuously declining release rate. A three-layer matrix with layers from the same polymeric material but with different solute concentrations in the inner and outer layers (–––) has considerably more uniform rate. Moreover, the use of a more permeable material in the inner layer (–––) results in more than 70% of embedded solute released at a practically constant rate (J. Membrane Sci., 343, 2009, 128-136)


Mechanisms of Micromolecular Non-Fickian Transport Kinetics in Glassy Polymers

Sorption kinetics in glassy polymer systems exhibits a variety of deviations from normal Fickian behaviour, attributable to either (i) slow viscous relaxations of the swelling polymer, or (ii) differential swelling stresses generated by the constraints imposed on local swelling during sorption. Our group develops models based on both mechanisms, capable of simulating all basic features of observed non-Fickian kinetic behaviour, including Case II kinetics. Experimental work includes (i) sorption from the vapour phase. Carefully designed experimental sorption protocols, supplemented by measurement of longitudinal swelling kinetics of the polymer film, enable us to study various types of non-Fickian behaviour. On the basis of the models mentioned above, we develop general diagnostic criteria for distinguishing between the underlying mechanisms responsible for the observed experimental behaviour. (ii) sorption from the liquid phase. Combination of various optical techniques enables us to study in detail various types of non-Fickian penetration such as stress-dependent diffusion and Case II kinetics.


Non-Fickian (deviating form t1/2 law) kinetics of Methylene chloride vapor sorption (●) in a cellulose acetate film. The operation of the Differential Swelling Stresses (DSS) mechanism is revealed by the concurrent longitudinal (□), and thickness (▽) dilation kinetics. Based on model predictions (Macromolecules, 34, 2001, 1400) the correlations of sorption-longitudinal dilation kinetics can be used as a diagnostic tool for identifying the viscoelastic behaviour of the glassy polymer in response to the DSS operating during a sorption experiment.



Polymer-based Chemical sensors

In collaboration with the Institute of Microelectronics in Demokritos, we evaluate the swelling behaviour polymeric materials in the form of thin supported films upon exposure to different vapour environments, for subsequent use as the sensing layer of chemocapacitive chemical sensors. The activity aims at the development of sensor arrays for specific applications concerning the detection of analytes in complex vapor environments.





Schematic side view of an InterDigitative Chemocapacitive (IDC) sensor. Vapor detection and measurement by Chemocapacitive sensors, is based on changes in the dielectric properties of the sensing polymeric material due to sorption of analytes


Experimental capacitance changes (ΔC/Co) of an IDC sensor, fabricated in the Institute of Microelectronics, NCRS ”Demokritos”, upon exposure to four vapor analytes of varying dielectric constant (ε) are compared to the predictions on dielectric constant changes (Δε/εo) of the polymer-analyte system, calculated by the Clausius-Mosotti mixing rule. The calculation was based on the corresponding experimental vapor-induced swelling (ΔL/Lo) of the polymeric films by use of white light reflectance spectroscopy (IEEE Sensors 2008, October 26-29, 2008, Lecce, Italy, Book of Abstracts, p.423-426)


Funded Projects (2005-)

  1. “Computer aided molecular design of multifunctional materials with controlled permeability properties-Multimatdesign”, FP6-NMP-STREP, 86 Κ€, 2005-2008.

  2. “Facing pathogenic conditions by combined use of bio-medical methods and nanotechnology” Ypodomes, Metro 4.5, 4.4.1 Action «Consortia of research and technological development in sectors of National priorities», 2050-4/2, 2005-2008.

  3. “Development of innovative bio-active magnetic nanomaterials for diagnosis and monitoring of pathogenic conditions by magnetic tomography”, PEP Attikis, 2006-2008.

  4. “Morphological control of polymer blend nanofilms for organic (opto-) electronics" Joint research and technology programmes, Greece -Poland, 2006 – 2008.

Infrastructure

Vacuum apparatuses for sorption and longitudinal dilation kinetic measurements on polymer samples including electronic microbalances (Cahn 2000 and MK2-M5 CI Electronics) or quartz spring balances, Polarizing and interferometric microscopes, Tensile tester in conjunction with optical setup, Thermal analysis instruments (Temperature Modulated DSC), Home-made apparatuses for kinetic release measurements, Abbe refractometer, Dissolution tester equipped with fraction collector and UV-Vis spectrophotometer (Jasco).



 
 
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